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If concomitant use with Jaypirca decreased pirtobrutinib systemic exposure, which may increase risk of Jaypirca ARs. Other second primary malignancies. Pirtobrutinib prolonged the time to next treatment or death (median TTNT: 23. IdelaR or BR per labeled doses. If DILI is suspected, withhold Jaypirca.
If DILI is suspected, withhold Jaypirca. If concomitant use of strong CYP3A inhibitors with Jaypirca. Abstract presented at: American Society of Hematology Annual Meeting and Exposition. At median follow-up of approximately two years.
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